Dr. Rajiv Kumar



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  • Profile
  • QualificationsM.Sc. , PhD. , Post Doc. (Queensland Institute of Medical Research-Australia)
  • DesignationDST INSPIRE Faculty
  • DivisionBiotechnology
  • Contact No.+91-9643906460/9935940735
  • E-Mailrajiv082@yahoo.com; itsrajaryan@gmail.com

Biosketch

Dr. Rajiv Kumar joined Div. of Biotechnology, NSIT as DST INSPIRE Faculty in June-2015. Before joining NSIT, he was in National Institute of Technology-Rourkela. A PhD from Banaras Hindu University (BHU) and visiting scientist at Queensland Institute of Medical Research (QIMR)-Brisbane, Australia, his current research interest is to understand the immune regulation during chronic parasitic infection (Malaria & Leishmaniasis) and primarily focused on addressing the role of regulatory cell surface molecules/receptors and regulatory cytokines in the pathogenesis of these diseases using experimental models as well human patients. He was awarded DST INSPIRE Faculty grant of Rs. 35 Lakhs in 2014 (for 5 years) for his project “Role of Tim-3/Galectin-9 in pathogenesis of Malaria/Leishmania”. He has made significant contributions to understanding of the pathogenesis of parasitic diseases which is exemplified by his impressive publication. So far he has 20 publications, all in high impact international journals like Nature Medicine, British Journal of Medicine, Journal of Immunology, Journal of Infectious Diseases, PLoS NTD etc with more than 375 citations.

Areas of Interest
  1. Immune Regulation during Parasitic infection (Role of Regulatory cytokines and cell surface.
  1. Bhattacharyya T, Ayandeh A, Falconar AK, Sundar S, El-Safi S, Gripenberg MA, Bowes DE, Thunissen C, Singh OP, Kumar R, Ahmed O, Eisa O, Saad A, Pereira SS, Boelaert M, Mertens P, Miles MA. IgG1 as a Potential Biomarker of Post-Chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test. PLoS Neglected Tropical Disease 2014 Oct 23; 8(10):e3273 [Impact Factor: 4.48, Citations : 01]. ISSN: 1935-2735

  2. Kumar R, Singh N, Gautam S, Singh OP, Gidwani K, Rai M, Sacks D, Sundar S, Nylen S. Leishmania specific CD4 T cells release IFNγ that limit parasite replication in patients with visceral leishmaniasis. PLoS Neglected Tropical Disease 2014 Oct 2; 8(10):e3198 [Impact Factor: 4.48]. ISSN: 1935-2735

  3. Kumar R, Singh OP, Gautam S, , Nylen S Sundar S. Enhanced expression of Toll like receptors 2 and 4 but not 9 in spleen tissue from patients with visceral leishmaniasis. Parasite Immunology 2014, 36 (12): 721-725. [Impact Factor: 2.14, Citations: 02] ISSN 0141-9838

  4. Bhattacharyya T,Bowes DE, El-Safi S, Sundar S,Falconar AK, Singh OP, Kumar R,Osman O, Boelaert M, Miles MA. Significantly lower anti-Leishmania IgG responses in Sudanese versus Indian visceral leishmaniasis. PLoS Neglected Tropical Disease 2014; 8(2): e2675 [Impact Factor: 4.48, Citation: 07] ISSN: 1935-2735

  5. Gautam S, Kumar R, Singh N, Singh A, Rai M, Sacks D, Sundar S, Nylen S. “CD8 T cell Exhaustion in Human Visceral Leishmaniasis”. Journal of Infectious Disease; 2014 15;209(2):290-9 [Impact Factor: 5.99, Citations : 16] ISSN: 0022-1899

  6. Faleiro RJ, Kumar R, Hafner LM, Engwerda CR. “Immune regulation during chronic visceral leishmaniasis”. PLoS Neglected Tropical Disease, 2014 Jul 10;8(7):e2914. [Impact Factor: 4.48, Citations: 02]. ISSN: 1935-2735

  7. Kumar R, Engwerda C. “Vaccines to prevent leishmaniasis”. Clinical & Translational Immunology (2014) 3, e13; doi:10.1038/cti.2014.4. [Citations : 14] ISSN: 2050-0068 (Nature Publishing Group)

  8. Engwerda C, Kumar R. “Mast Cell Fuel the Fire of Malaria Immunopathology”.Nature Medicine. 2013; 19 (6): 672-674. [Impact Factor: 28.05] ISSN: 1078-8956

  9. Singh OP, Gidwani K, Kumar R, Jones S, Boelaert M, Sacks D, Sundar S. "A reassessment of immune correlates in human visceral leishmaniasis as defined by cytokine release in whole blood" . Clinical and Vaccine Immunology 2012; 19(6):961-966.[Impact Factor: 2.37, Citations : 28]. ISSN: 1556-6811

  10. Kumar R, Nylén S. “Immuno-biology of Visceral Leishmaniasis”. Front Immunol. 2012; 3:251. [Citations : 28] ISSN: 1664-3224

  11. Chakaravorty J, Kumar S,Kumar R, Gautam S, Sundar S. Evaluation of rK39 immunochromatographic test with urine for diagnosis of visceral leishmaniasis.Transactions of Royal Society of Tropical Medicine and Hyegiene 2011 Sep; 105(9):537-539. [Impact Factor: 1.93, Cations: 05]. ISSN: 0035-9203

  12. Gautam S*,Kumar R*, Maurya R*, Nylén S, Ansari N, Rai M, Sundar S, Sacks D. Direct demonstration of the anti-parasitic effect of IL-10 inhibition in splenic aspirates from patients with visceral leishmaniasis. Journal of Infectious Disease 2011: Oct 1; 204(7):1134-1137 (*Joint 1st Author). [Impact Factor: 5.99, Citations:50] ISSN: 0022-1899

  13. Ansari N*,Kumar R*, Gautam S, Nylén S, Singh OP, Sundar S, Sacks D. IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis. Journal of Immunology 2011: Apr 1; 186(7):3977-3985 (*Joint 1st Author). [Impact Factor: 5.36, Citations: 58]. ISSN:

  14. Gidwani K, Jones S, Kumar R, Boelaert M, Sundar S. Interferon-gamma Release Assay (modified QuantiFERON®) as a potential marker of infection for Leishmania donovani, a proof of concept study. PLoS Neglected Tropical Disease 5 (4): e1042. [Impact Factor: 4.48, Citations: 21]. ISSN: 1935-2735

  15. Gidwani K, Picado A, Ostyn B, Singh SP, Kumar R, Khanal B, Lejon V, Chappuis F, Boelaert M, Sundar S. Persistence of Leishmania donovani antibodies in past visceral leishmaniasis cases in India. Clinical and Vaccine Immunology 2011; 18(2):346-348. [Impact Factor: 2.37, Citations : 19] ISSN: 1556-6811

  16. Picado A, Singh SP, Rijal S, Sundar S, Ostyn B, Chappius F, Uranw S, Gidwani K,Khanal B, Kumar R, Srivastav P, Dujardin JC, Boelaert M. Longlasting insecticidal nets for prevention of Leishmania donovani infection in India and Nepal: paired cluster randomized trial. British Medical Journal 2010; 341:c6760. [Impact Factor: 17.44, Citations : 44] ISSN 1756-1833

  17. Maurya R, Kumar R, Prajapati VK, Manandhar KD, Sacks D, Sundar S, Nylén S. “Human visceral leishmaniasis is not associated with expansion or accumulation of Foxp3+ CD4 cells in blood or spleen”. Parasite Immunology 2010;32: 479-483. [Impact Factor: 2.14, Citations : 13] ISSN 0141-9838

  18. Kumar R, Goto Y, Gidwani K, Cowgill KD, Sundar S, Reed SG. “Evaluation of ex vivo Human Immune Response Against Candidate Antigens for a Visceral Leishmaniasis Vaccine”. American Journal of Tropical Medicine and Hygiene 2010; 82(5): 808-813. [Impact Factor: 2.74, Citations : 15] ISSN: 0002-9637

  19. Clements MF*,Gidwani K*,Kumar R*, Hostomska J, Dinesh D, Kumar V, Das P, Müller I, Hamilton G, Volfova V, Boelaert M, Das M, Rijal S, Picado A, Volf P, Sundar S, Davies CR, Rogers ME. “Measurement of recent exposure to Phlebotomus argentipes, the vector of Indian visceral leishmaniasis, By Using Human Antibody Responses to Sand Fly Saliva”. Americal Journal of Tropical Medicine and Hygiene 2010; 82(5): 801-807. (* Equal contribution) [Impact Factor: 2.74, Citations : 30] ISSN: 0002-9637

  20. Gidwani K, Kumar R, Rai M, Sundar S. “A Longitudinal Sero-epidemiologic Study of Visceral Leishmaniasis in Hyperendemic Region of Bihar, India”. American Journal of Tropical Medicine and Hygiene 2009; 80(3): 345-346. [Impact Factor: 2.74, Citations : 22] ISSN: 0002-9637